<\/b><\/p>\n
<\/b><\/p>\n
WEDNESDAY, Sept. 30, 2020 (HealthDay News) — Decreased colorectal cancer (CRC) incidence is seen in association with use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), magnesium, folate, and high consumption of fruits and vegetables, fiber, and dairy products, according to an umbrella review published online Sept. 28 in Gut<\/i>.<\/p>\n
Nicolas Chapelle, M.D., from the Institut des Maladies de l’Appareil Digestif in Nantes, France, and colleagues examined evidence from 80 meta-analyses of interventional and observational studies of CRC prevention using medications, vitamins, supplements, and dietary factors to examine the ideal chemopreventive agent or agents.<\/p>\n
Based on a review of the literature, the researchers found suggestions for a decreased incidence of CRC with the use of aspirin, NSAIDs, magnesium, folate, a high consumption of fruits and vegetables, fiber, and dairy products. There was an increased CRC incidence observed with frequent alcohol or meat consumption. There was no evidence of a protective effect for tea, coffee, garlic, fish, or soy products. A moderate level of evidence was found for aspirin, \u03b2-carotene, and selenium, while for all other exposures or interventions, the level of evidence was low or very low.<\/p>\n
“It is our hope that despite all aforementioned limitations, this comprehensive umbrella meta-analysis will assist clinicians in counselling patients, and help to guide the future research on the topic that is required in many instances, to better characterize the impact of a nutritional, supplement, or chemical intervention in CRC prevention in an average-risk population,” the authors write.<\/p>\n