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TUESDAY, Oct. 6, 2020 (HealthDay News) — Continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea optimally used at night reduces resting heart rate during the day, according to a study published online Oct. 1 in the Journal of the American Heart Association<\/i>.<\/p>\n
Sushmita Pamidi, M.D., from the McGill University Health Centre in Montreal, and colleagues randomly assigned 39 participants with obstructive sleep apnea (OSA) and prediabetes to either in-laboratory all-night CPAP or an oral placebo for two weeks. For 19 consecutive days and nights, resting heart rate was continuously assessed using an ambulatory device.<\/p>\n
The researchers found that compared with placebo, CPAP reduced daytime resting heart rate (treatment difference, \u22124.1 beats\/min). Significant correlations were noted between the magnitude of reduction in daytime resting heart rate after treatment and the magnitude of decrease in plasma norepinephrine, a marker of sympathetic activity, as well as the magnitude of decrease in OSA severity.<\/p>\n
“These findings suggest that better identification and treatment of OSA may have important clinical implications for cardiovascular disease prevention,” the authors write.<\/p>\n