Decrease in lumbar volumetric bone mineral density seen in obese teens undergoing sleeve gastrectomy<\/p>\n<\/h3>\n
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WEDNESDAY, Dec. 2, 2020 (HealthDay News) — Adolescents with obesity undergoing sleeve gastrectomy (SG) have a decrease in lumbar volumetric bone mineral density (vBMD), which is associated with increased lumbar marrow adipose tissue (MAT), according to a study presented at the annual meeting of the Radiological Society of North America, held virtually from Nov. 29 to Dec. 5.<\/p>\n
Miriam A. Bredella, M.D., from Harvard Medical School in Boston, and colleagues examined 52 adolescents with moderate-to-severe obesity: 26 followed before and 12 months after SG and 26 nonsurgical controls followed for 12 months.<\/p>\n
The researchers found that adolescents who underwent SG lost 34 \u00c2\u00b1 13 kg, while there was no significant weight change in the control group. Compared with controls, there was a significant decrease in vBMD measured by quantitative computed tomography in the SG group. Within the SG group, there was an increase in lumbar MAT; compared with controls, the difference was not significant. Compared with controls, the SG group had a significant decrease in MAT content of the femur and tibia. An inverse association was seen between 12-month change in lumbar vBMD and lumbar MAT; no association was seen between the change in vBMD and peripheral MAT.<\/p>\n
“Adolescents who underwent sleeve gastrectomy had bone loss and an increase in bone marrow fat, despite marked loss of body fat,” Bredella said in a statement. “While weight-loss surgery is successful for weight loss and improving metabolic disorders, it has negative effects on bone.”<\/p>\n
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