Risk factors include peripheral sensory neuropathy, peripheral arterial disease, nephropathy, and poor glycemic control<\/p>\n<\/h3>\n
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TUESDAY, Jan. 26, 2021 (HealthDay News) — Hospitalizations for diabetes-related foot ulcers (DFUs) are increasing, according to a study published online Jan. 13 in Diabetes Care<\/em>.<\/p>\n Emma J. Hamilton, Ph.D., from the University of Western Australia in Perth, and colleagues used data from the Fremantle Diabetes Study phases I (FDS1; 1,296 participants, recruited 1993 to 1996) and II (FDS2; 1,509 participants, recruited 2008 to 2011). Participants were followed from entry to first hospitalization for or with DFU, death, or five years.<\/p>\n The researchers found that incident DFU hospitalization was 1.9 per 1,000 person-years in FDS1 and 4.5 per 1,000 person-years in FDS2. The crude incident rate ratio was 2.40, and the incident rate difference was 2.6 per 1,000 person-years. FDS2 participants aged 31 to 40 years had the highest incident rate for any age group (23.6 per 1,000 person-years). Independent predictors of incident hospitalization for or with DFU included age at diabetes diagnosis (inverse), hemoglobin A1c, insulin use, height, ln(urinary albumin\/creatinine), absence of any foot pulse, previous peripheral revascularization, and peripheral sensory neuropathy (PSN).<\/p>\n “Incident DFU hospitalizations complicating type 2 diabetes increased between FDS phases, especially in younger participants, and were more likely in those with PSN, peripheral arterial disease, and suboptimal glycemic control at baseline,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n