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TUESDAY, Aug. 13, 2019 (HealthDay News) — General and abdominal adiposity are associated with mortality in a population of Mexican adults, according to a study published online Aug. 13 in the Annals of Internal Medicine<\/i>.<\/p>\n
Louisa Gnatiuc, from the University of Oxford in the United Kingdom, and colleagues examined the causal relevance of adiposity to mortality in Mexican adults in a prospective study involving 115,400 adults aged 35 years to <75 years at recruitment and followed for 14 years.<\/p>\n
The researchers observed a J-shaped correlation for body mass index (BMI) at recruitment with all-cause mortality, with the minimum at 25 to <27.5 kg\/m\u00b2. Above 25 kg\/m\u00b2, there was a 30 percent increase in mortality for each 5-kg\/m\u00b2 increase in BMI (hazard ratio, 1.30). The correlation was stronger at ages 40 to <60 years than at ages 60 to <75 years (hazard ratios, 1.40 and 1.24, respectively). Sex, smoking, and other confounders did not materially affect the correlation. Similarly, strong associations were seen for mortality with BMI and waist-to-hip ratio; each was attenuated only slightly by adjustment for the other. There was a strong correlation for waist circumference with mortality, which persisted even after adjustment for BMI and hip circumference.<\/p>\n
“We also found that given BMI, the waist-to-hip ratio remains of substantial additional relevance to mortality, suggesting that central obesity is particularly harmful,” the authors write.<\/p>\n
Several authors disclosed financial ties to the pharmaceutical industry.<\/p>\n
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