A 5-year-old boy presented with generalized cutaneous erosions, severe scarring, depigmentation and contractures affecting major joints. The lesions had initially affected his ears, nose, feet, and the genital and ocular …
Fecal Transplant May Counter Anti-PD-1 Resistance in Melanoma
FMT plus anti-PD-1 therapy may change gut microbiome and help overcome drug resistance in some patients with advanced melanoma
Prevalence Data Suggest Increasing Trend of Psoriasis With Age
Worldwide studies suggest stable or slightly decreasing trend in incidence of psoriasis and increasing trend in prevalence
Noninflammatory comedones have greater diversity in microbiome and are more prone to biofilm formation than inflammatory lesions of acne vulgaris.
The ability of Cutibacterium acnes strains to form biofilms has been correlated with their virulence.This study examined biofilm and skin microbiota in acne patients in order to understand their role …
Trends in the management of hidradenitis suppurativa in the Middle East region: a systematic review.
Hidradenitis suppurativa (HS) is a chronic, painful, and severely debilitating inflammatory disease that affects apocrine gland-bearing skin. There is no universal consensus on the management of hidradenitis suppurativa (HS). Current …
Trichoscopic features of tinea capitis among primary school children in north central Nigeria.
The myriad of coexisting risk factors for tinea capitis (TC) in parts of Africa makes it common among schoolchildren from this region. Diagnosis ideally involves microscopy and culture of scalp …
Metformin is associated with decreased risk of basal cell carcinoma: A whole-population case-control study from Iceland.
Metformin has anti-carcinogenic properties and is also known to inhibit the Sonic hedgehog pathway, but no population-based studies exist analyzing the potential protective effect for basal cell carcinoma (BCC) and …
Medical imaging examination in psoriasis and early psoriatic arthritis patients: an updated systematic review and meta-analysis.
Psoriatic arthritis appears in one in four skin psoriasis patients. Early detection of the presence of joint involvement and early interception of its developments may minimize long-term functional disability, and the …
Immunohistochemical analysis of the expression of selected cell lineage markers (CD4, CD8, CD68, c-Kit, Foxp3, CD56, CD20) in cutaneous variant of lichen planus.
Lichen planus (LP) is considered to be an immune-mediated disease of a not fully understood etiology. There are scarce data on the immune cells forming the band-like infiltration in cutaneous …
The status and outcomes of registered clinical trials for JAK inhibitors in alopecia areata: are non-published trials being overlooked?
Recent meta-analyses of Janus kinase (JAK) inhibitors in alopecia areata (AA) have excluded trial registries and may thus be subject to publication bias. This study assessed the potential for evidence …