The study objective was to examine if age and chronic environmental exposure affect the water content and the composition of the natural moisturizing factors (NMFs) of the stratum corneum (SC).Forty …
Dermatology Patients Pleased With Telehealth Options
Patients report telehealth consultations are safe and efficient during the COVID-19 pandemic
Risk of macrophage activation syndrome in adult-onset Still’s disease patients with skin involvement: A retrospective cohort study.
Small case series and case reports indicated atypical persistent pruritic eruptions (PPEs), another type of skin lesions in adult-onset Still’s disease (AOSD), imply a worse prognosis than typical evanescent rashes.To …
Simvastatin in vitiligo: an update with recent review of the literature.
Patients with vitiligo often seek medical attention, as it diminishes their quality of life resulting in significant morbidity. Several topical and systemic therapies are in vogue targeting the immunological aspect …
Association of the Affordable Care Act’s Medicaid Expansion with the diagnosis and treatment of clinically localized melanoma: A National Cancer Database Study.
The Affordable Care Act’s Medicaid expansion is associated with earlier diagnosis and improved care among lower socioeconomic status populations with cancer, but its impact on melanoma is undefined.To determine the …
Downregulation of SHANK-associated RH domain-interacting protein elevates interleukin-33 expression by stimulating the Janus kinase 2/signal transducer and activator of transcription signaling pathway in HaCaT cells.
Atopic dermatitis (AD) is a chronic inflammatory skin disease in which T-helper type 2 (Th2 ) immune responses are dominant. SHANK-associated RH domain interacting protein (SHARPIN) is expressed at low levels …
How prevalent are financial conflicts of interest in dermatology randomised controlled trials? A cross-sectional study.
Several countries have introduced transparency databases since the last assessment of conflicts of interest (COIs) in dermatology randomised controlled trials (RCTs) in 2004. We assessed the prevalence of financial COIs …
Somatostatin receptors: an alternative treatment target for advanced Merkel cell carcinoma.
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high risk of returning and spreading. It affects about 2500 new patients every year in the USA. …
Five-year efficacy and safety of tildrakizumab in patients with moderate to severe psoriasis who respond at week 28: pooled analyses of two randomised phase 3 clinical trials (reSURFACE 1 and reSURFACE 2).
The phase 3 reSURFACE 1 and reSURFACE 2 (NCT01722331/NCT01729754) trials of the anti-interleukin-23p19 monoclonal antibody tildrakizumab for psoriasis treatment are complete.We present 5-year pooled data from reSURFACE 1 and reSURFACE …
Drug survival of Adalimumab and Infliximab in Hidradenitis Suppurativa Patients: A Daily Practice Cohort Study.
Biologics are often required for treatment of hidradenitis suppurativa (HS). However, data on the drug survival of biologics in daily practice are currently lacking.To assess the drug survival of anti-TNF …