Palmoplantaris pustulosis (PPP) is a chronic relapsing skin condition characterized by sterile pustules on the palm and soles. Population-based estimates of PPP incidence and prevalence are limited.To estimate the prevalence …
Signaling of multiple IL-17 family cytokines through IL-17RA drive psoriasis-related inflammatory pathways.
The IL-23/IL-17 immune axis is of central importance in psoriasis. However, the impact of IL-17 family cytokines other than IL-17A in psoriasis has not been fully established.To elucidate the contribution …
Ca2+ signalling is critical for autoantibody-induced blistering of human epidermis in pemphigus.
Pemphigus is a severe bullous autoimmune skin disease. Pemphigus foliaceus (PF) is characterized by anti-desmoglein(DSG)-1-IgG causing epidermal blistering, mucosal pemphigus vulgaris (mPV) by anti-DSG-3-IgG inducing erosions in the mucosa, and …
Community Exposures Tied to SARS-CoV-2 Seropositivity in HCWs
Workplace factors not linked to seropositivity for health care personnel
Upadacitinib Beats Placebo for Psoriatic Arthritis
Percentage of patients with ACR20 response significantly higher with upadicitinib versus placebo at week 12
Change in lentigo maligna score assessed by in vivo reflectance confocal microscopy after one month of imiquimod treatment for lentigo maligna management.
Treatment of Lentigo Maligna (LM) is challenging because of the potential functional and esthetic surgical sequelae. Imiquimod has been proposed as an alternative treatment for LM. Reflectance Confocal Microscopy (RCM) …
Clinical, biochemical and serological predictors of DRESS syndrome: a prospective case-control study.
Although detailed scoring systems like RegiSCAR DRESS validation score are available to diagnose DRESS syndrome, a rapid and easily applicable tool to identify DRESS at presentation is lacking.To identify the …
Obesity Tied to Increased Mortality Overall in Patients With Cancer
Risk for death lower for patients with lung cancer, renal cell carcinoma, melanoma with versus without obesity
The Association between Citrus Consumption and Melanoma Risk in the UK Biobank.
Melanoma incidence has been dramatically increasing worldwide. Psoralen, a known photocarcinogen, is naturally abundant in citrus products, leading to the hypothesis that high citrus consumption may increase melanoma risk.To investigate …
Psoriasis Linked to Higher Risk for Thyroid Disease
Psoriasis also associated with higher odds of thyroid dysfunction