Poikiloderma is a skin condition that combines atrophy, telangiectasia, and macular pigment changes (hypo- as well as hyperpigmentation). It is often mistaken for mottled pigmentation by general practitioners or nondermatology …
Journal attitudes and outcomes of preprints in dermatology.
The use of preprints, manuscripts that can be uploaded to a public server and made almost immediately available for public dissemination without peer review, is becoming increasingly common.1 Preprint servers …
Management of skin thinning and aging: review of therapies for neocollagenesis; hormones and energy devices.
Hormone replacement therapy and various devices exist to treat signs of aging, such as skin thinning, yet there are no reviews summarizing or evaluating their role in neocollagenesis and the …
Managing pain associated with dermatologic procedures.
Dermatologists are faced with an aging population, accompanied by an increase in the incidence of skin cancer, especially nonmelanoma skin cancer. With this increase in cutaneous malignancy comes an increase …
Mycophenolate mofetil as adjunctive therapy to corticosteroids for the treatment of pyoderma gangrenosum: a case series and literature review.
Pyoderma gangrenosum is a rare neutrophilic dermatosis that is commonly treated with systemic corticosteroids; however, their potent side effects may warrant tapering, and non-steroidal systemic immunosuppressants may help maintain or …
Oral corticosteroid bursts and severe adverse events: a critical appraisal.
Short-term corticosteroids are commonly used to treat various dermatoses. Previous study has indicated oral corticosteroids < 30 days duration increased the risk of gastrointestinal (GI) bleedings, fractures, venous thromboembolism and sepsis.1 …
High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types.
High tumor mutation burden (TMB-H) has been proposed as a predictive biomarker for response to immune checkpoint blockade (ICB), largely due to the potential for tumor mutations to generate immunogenic …