Palmoplantaris pustulosis (PPP) is a chronic relapsing skin condition characterized by sterile pustules on the palm and soles. Population-based estimates of PPP incidence and prevalence are limited.To estimate the prevalence …
Signaling of multiple IL-17 family cytokines through IL-17RA drive psoriasis-related inflammatory pathways.
The IL-23/IL-17 immune axis is of central importance in psoriasis. However, the impact of IL-17 family cytokines other than IL-17A in psoriasis has not been fully established.To elucidate the contribution …
Ca2+ signalling is critical for autoantibody-induced blistering of human epidermis in pemphigus.
Pemphigus is a severe bullous autoimmune skin disease. Pemphigus foliaceus (PF) is characterized by anti-desmoglein(DSG)-1-IgG causing epidermal blistering, mucosal pemphigus vulgaris (mPV) by anti-DSG-3-IgG inducing erosions in the mucosa, and …
Community Exposures Tied to SARS-CoV-2 Seropositivity in HCWs
Workplace factors not linked to seropositivity for health care personnel
Upadacitinib Beats Placebo for Psoriatic Arthritis
Percentage of patients with ACR20 response significantly higher with upadicitinib versus placebo at week 12