Significant variation exists in the surgical suture materials and techniques used for dermatological surgery. Many wound closure techniques are now practiced including use of sutures, staples and topical adhesives. The …
Health-related quality of life and economic burden of prurigo nodularis.
Prurigo nodularis (PN) is an understudied, pruritic inflammatory skin disease. Little is known about the effect of PN on quality of life (QoL) and its associated economic burden.To quantify QoL …
Intravascular histiocytosis: mimicker of cellulitis, angiosarcoma, inflammatory breast cancer, and others.
Intravascular histiocytosis is an underrecognized reactive skin condition characterized by the clinical finding of poorly demarcated erythematous to violaceous patches and plaques. The diagnosis is confirmed by the histologic findings …
NOD2 signalling in hidradenitis suppurativa.
Hidradenitis suppurativa (HS) is associated with dysregulated immune responses including altered expression of cytokines, chemokines, and antimicrobial peptides and proteins (AMPs).To evaluate the expression of NOD2 and related factors in …
Mycosis fungoides-derived exosomes promote cell motility, are enriched with miR-155 and miR-1246, and their plasma cell-free expression may serve as potential biomarkers for disease burden.
Literature regarding exosomes as mediators in intercellular communication to promote progression in mycosis fungoides (MF) is lacking.To characterize MF-derived exosomes and their involvement in the disease.Exosomes were isolated by ultracentrifugation …
Association of Single Nucleotide Polymorphisms in the CXCR1, CXCR2 and CXCL5 with the Behçet’s Disease in Denizli Province of Turkey.
Behçet’s disease (BD) is associated with the immune system, especially neutrophilic activity. The CXCR1, CXCR2 and CXCL5 mediate the activation and migration of the neutrophils.The aim of our study was …
Sebaceous tumours: A prototypical class of skin tumour for universal germline genetic testing.
Lynch syndrome (LS) is an adult-onset cancer predisposition caused by a germline pathogenic variant affecting one of four mismatch repair (MMR) genes (MLH1, MSH2, MSH6, or PMS2). The vast majority …
Diagnosing muscle disease in a cohort of classic dermatomyositis patients seen at a rheumatologic dermatology outpatient clinic.
Existing criteria include muscle biopsies to improve the probability of capturing dermatomyositis (DM), but not much is known whether less invasive diagnostic procedures may be just as useful.We aim to …
ASCO: Nivolumab, Relatlimab Combo Slows Advanced Melanoma
Median progression-free survival of 10.1 versus 4.6 months seen among those receiving combo versus nivolumab alone, respectively
Many Americans Confused About Sunscreens: Poll
AAD poll highlights common misconceptions about sunscreen application