EPHB4 and its ligand, ephrin B2, which are receptor tyrosine kinases of the erythropoietin-producing hepatocellular (EPH) family, are known to be linked to several human cancers. The aim of this …
Baricitinib in patients with moderate-to-severe atopic dermatitis: Results from a randomized monotherapy Phase 3 trial in the United States and Canada (BREEZE-AD5).
Baricitinib, an oral, selective Janus kinase (JAK)1/JAK2 inhibitor, is being studied for moderate-to-severe atopic dermatitis (AD) in adults.To evaluate the efficacy and safety of baricitinib monotherapy in a North American …
Discoid lupus erythematosus solely involving the eyelids: case report and literature review.
The involvement of eyelids occurs in only 5-6% of patients with discoid lupus erythematosus (DLE), commonly with mucocutaneous lesions elsewhere. DLE solely involving the eyelids is relatively rare. This study …
Overall Pregnancy, Live Birth Outcomes Unchanged in Psoriasis
Of the births, 90.9 percent born full term, 9.1 percent born prematurely; few had neonatal problem or congenital anomaly
Factors Other Than Workplace Tied to COVID-19 Positivity in HCWs
Demographic, community factors show stronger influence than workplace exposure on COVID-19 risk in health care workers
ICI Need Not Be Withheld in Those With Autoimmune Disease
Objective response rates to anti-CTL4, anti-PD-1, combination similar for advanced melanoma patients with, without AID
Phacomatosis spilosebacea: A new name for a distinctive binary genodermatosis.
Phacomatosis pigmentokeratotica (PPK) is defined by the association of papular nevus spilus arranged in a flag-like pattern and sebaceous nevus following Blaschko’s lines. A systematic search of the worldwide literature retrieved …
Circulating tumour DNA in patients with advanced melanoma treated with dabrafenib or dabrafenib plus trametinib: a clinical validation study.
Melanoma lacks validated blood-based biomarkers for monitoring and predicting treatment efficacy. Cell-free circulating tumour DNA (ctDNA) is a promising biomarker; however, various detection methods have been used, and, to date, …
Slack as a virtual undergraduate dermatology community: a pilot.
Dermatology is recognised as under-represented in UK undergraduate curricula. With a diagnostic and educational toolkit that is heavily centred on face-to-face clinical examination, dermatology education has been disproportionately affected by …
Investigating the presence of neutrophil extracellular traps in septal and lobular cutaneous panniculitides.
Panniculitides are a heterogeneous group of inflammatory dermatoses involving the subcutaneous fatty tissue. Histologically, they are classified into septal and lobular panniculitis, according to the predominant localization of the inflammatory …