Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits both interleukin-17A and interleukin-17F. The efficacy and safety of bimekizumab as compared with secukinumab, which selectively inhibits interleukin-17A alone, in patients …
Salt and skin.
The introduction of salt as a therapeutic agent in dermatological disorders has been in use since ancient times. This ubiquitous agent is the most underrated substance after the advent of …
Clinical Impact of Immunotherapy in Merkel Cell Carcinoma patients: A Systematic Review and Meta-Analysis.
Immunotherapy is emerging as an alternative for Merkel cell carcinoma (MCC), but its long-term effects on response, survival, and safety are not well established. High-quality evidence is needed to estimate …
YouTube as a source of educational information for natural hair.
There has been a rise in popularity of natural hair, a movement normalizing afro-textured hair in its natural state, without chemical or heat alteration. It is thought that genetic predisposition …
The chameleon rash: a review of the polyphenotypic dermatoses of dermatomyositis.
Dermatomyositis (DM) is an autoimmune connective tissue disease which is included in the idiopathic inflammatory myopathies. Cutaneous manifestations are a prominent part of the condition: some skin signs in DM …
Stimulant use in patients presenting with psychocutaneous disorders.
Psychocutaneous disorders are often attributed to stimulant medications, yet this relationship has never been fully elucidated. Literature on psychocutaneous disorders largely focuses on clinical presentation and treatment rather than disease …
Hand eczema and temporal variation of Staphylococcus aureus clonal complexes: A prospective observational study.
Hand eczema (HE) is frequently colonized with Staphylococcus aureus (S. aureus); however, its role in the pathogenesis of HE is poorly understood.To investigate temporal variation of S. aureus sub-types, i.e. …
Study of melanocyte density and epidermal thickness in vulvar lichen sclerosus lesions.
This study aimed to analyze changes in melanocyte density and epidermal thickness in vulvar lichen sclerosus (VLS).Vulvar skin tissues were collected from 15 VLS female patients in Beijing Hospital, classified …
Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial.
The antimelanogenesis effect of topical and oral glutathione has been shown in several in vitro and clinical studies. However, whether combination of topical and oral glutathione is superior to topical …
Limitations in the Literature Regarding Mohs Surgery and Staged Excision for Melanoma: A Critical Review of Quality and Data Reporting.
The literature supporting Mohs micrographic surgery (MMS) and staged excision (SE) in treating primary cutaneous melanoma is growing but has not been critically reviewed for bias.Articles concerning MMS/SE for melanoma …