Psoriasis is a stigmatizing disease that often affects female patients more negatively than male patients. Very little systematic data on the treatment responses related to gender exists.This two-country, multi-centre, prospective, …
Histopathological and immunohistochemical features of facial papules in frontal fibrosing alopecia.
Facial papules (FPs) are considered to be created by the inflammatory process involving facial vellus hairs in frontal fibrosing alopecia (FFA).This study aimed to demonstrate the histopathological features of FPs …
NB-UVB phototherapy is associated with a reduction in topical corticosteroid and clinical improvement in atopic dermatitis – a historical inception cohort study.
Despite decades of use, the magnitude of efficacy of narrowband-ultraviolet B phototherapy (NB-UVB) for atopic dermatitis (AD) outwith industry-sponsored trials remains unclear.To evaluate the clinical efficacy of NB-UVB in AD …
Ultraviolet A Radiation and COVID-19 Deaths in the USA with replication studies in England and Italy.
Understanding factors impacting deaths from COVID-19 is of the highest priority. Seasonal variation in environmental meteorological conditions affects the incidence of many infectious diseases and may also affect COVID-19. Ultraviolet …
What is the best surgical treatment for dermatofibrosarcoma protuberans?
Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing skin cancer that is primarily treated with surgery. Because this cancer can spread deep into the skin and surrounding tissue in an irregular …
Intrapartum Group B Streptococcal Prophylaxis and Childhood Allergic Disorders.
To determine if maternal intrapartum group B Streptococcus (GBS) antibiotic prophylaxis is associated with increased risk of childhood asthma, eczema, food allergy, or allergic rhinitis.Retrospective cohort study of 14 046 children. …
Cell signaling in cutaneous T-cell lymphoma microenvironment: promising targets for molecular-specific treatment.
Cutaneous T-cell lymphomas (CTCL) result from the infiltration and proliferation of a population of T cells in the skin, inducing changes in the activity of both T cells and surrounding …
Development of a shared decision-making tool in vitiligo: an international study.
Shared Decision-Making tools (SDMt) are visual tools developed to promote joint medical decision-making between physician and patient. In dermatology, there is a paucity of such tools.To develop and validate a …
Defining Trajectories of Response in Psoriasis Patients Treated with Biologic Therapies.
The effectiveness and cost-effectiveness of biologic therapies for psoriasis are significantly compromised by variable treatment responses. Thus, more precise management of psoriasis is needed.We aim to identify subgroups of psoriasis …
The risk of malignancy in secukinumab-treated psoriasis, psoriatic arthritis and ankylosing spondylitis patients: analysis of up to five-year clinical trial and post-marketing surveillance data.
Data on the use of biologic therapy and malignancy risk are inconsistent due to limited long-term robust studies.To assess the malignancy risk in secukinumab-treated psoriasis, psoriatic arthritis (PsA) and ankylosing …