Palmoplantaris pustulosis (PPP) is a chronic relapsing skin condition characterized by sterile pustules on the palm and soles. Population-based estimates of PPP incidence and prevalence are limited.To estimate the prevalence …
Signaling of multiple IL-17 family cytokines through IL-17RA drive psoriasis-related inflammatory pathways.
The IL-23/IL-17 immune axis is of central importance in psoriasis. However, the impact of IL-17 family cytokines other than IL-17A in psoriasis has not been fully established.To elucidate the contribution …
Change in lentigo maligna score assessed by in vivo reflectance confocal microscopy after one month of imiquimod treatment for lentigo maligna management.
Treatment of Lentigo Maligna (LM) is challenging because of the potential functional and esthetic surgical sequelae. Imiquimod has been proposed as an alternative treatment for LM. Reflectance Confocal Microscopy (RCM) …
Clinical, biochemical and serological predictors of DRESS syndrome: a prospective case-control study.
Although detailed scoring systems like RegiSCAR DRESS validation score are available to diagnose DRESS syndrome, a rapid and easily applicable tool to identify DRESS at presentation is lacking.To identify the …
The Association between Citrus Consumption and Melanoma Risk in the UK Biobank.
Melanoma incidence has been dramatically increasing worldwide. Psoralen, a known photocarcinogen, is naturally abundant in citrus products, leading to the hypothesis that high citrus consumption may increase melanoma risk.To investigate …
Clinicoprognostic implications of head and neck involvement by mycosis fungoides: A retrospective cohort study.
The clinicoprognostic implications of head and neck involvement of mycosis fungoides (MF) are poorly understood.To evaluate the association of head and neck involvement on the clinicoprognostic features of MF.The clinical …
Novel adjuvant options for cutaneous melanoma.
Patients with resected stage III and IV melanoma have a high risk of recurrence. As the outcomes for patients with metastatic disease have improved dramatically over the last decade due …
ONCOLYTIC VIRUS IN GLIOMAS: A REVIEW OF HUMAN CLINICAL INVESTIGATIONS.
Gliomas remain one of the more frustrating targets for oncologic therapy. Glioma resistance to conventional therapeutics is a product of their immune-privileged milieu behind the blood-brain barrier, in addition to …
A study of the microbiological profile of filler-induced skin necrosis.
Skin necrosis is one of the most severe complications following filler injections that results in permanent aesthetic defects. Although an increasing number of studies have addressed the management of dermal …
Ocular and auditory abnormalities in vitiligo patients: A case- control study.
Vitiligo is characterized by the destruction of functional melanocytes in the skin. This destruction could target melanocytes anywhere in the body, which could affect function of organs where they reside. …