Atopic dermatitis (AD) disease activity and severity is highly variable during childhood. Early attempts to identify subtypes based on disease trajectory have assessed AD presence over time without incorporating severity.To …
Oral dimethyl fumarate induces changes within the peripheral neutrophil compartment of psoriasis patients that are linked with skin improvement.
Dimethyl fumarate (DMF) is a treatment for moderate-to-severe psoriasis and multiple sclerosis. DMF therapy typically improves skin inflammation within the first 3 months of treatment. DMF is a prodrug that …
Balloon cell melanoma: a systematic review.
Balloon cell melanoma (BCM) is a rare presentation of malignant melanoma characterized by large, foamy melanocytes lacking pigmentation. This is a comprehensive review of the clinical, dermoscopic, and histological features …
Deodorants and antiperspirants: identification of new strategies and perspectives to prevent and control malodor and sweat of the body.
Excessive sweating and body odors in many cultures can cause negative perceptions of an individual and in many cases is related to poor hygiene. Personal hygiene products have been developed …
Visible Light Part I. Properties and Cutaneous Effects of Visible Light.
Approximately fifty percent of sunlight reaching the Earth’s surface is visible light (400-700 nm). Other sources of visible light include lasers, light-emitting diodes (LEDs), and flash lamps. Photons from visible …
Visible Light Part II. Photoprotection against visible and ultraviolet light.
Cutaneous photobiology studies have focused primarily on the UV portion of the solar spectrum. However, VL comprises 50% of EMR that reaches the earth’s surface, and, as discussed in Part …
Erythroderma (exfoliative dermatitis) part one: underlying causes, clinical presentation and pathogenesis.
Erythroderma (exfoliative dermatitis), first described by Von Hebra in 1868, manifests as a cutaneous inflammatory state, with associated skin barrier and metabolic dysfunctions. The annual incidence of erythroderma is estimated …
Bare necessities? The utility of full skin examination in the COVID19 era.
Full skin examination (FSE) may improve the detection of malignant melanoma (MM). The objective of this study was to assess the safety of targeted lesion examination (TLE) compared to FSE …
Chloracne: a case series on cutaneous expression of CYP1A1 as diagnostic biomarker.
The term dioxin is commonly used to describe a group of ubiquitous environmental contaminants: polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs, 209 different compounds). The best studied compound among the group …
Genital premalignant and malignant diseases: a retrospective study of male genital skin biopsies.
Genital skin malignancies are a rare entity encountered by clinicians that may result in significant morbidity and mortality. Lack of familiarity or expertise in this area among clinicians can delay …