Despite approximately 4,400 unresectable U.S. cases annually, high-stage basal cell carcinoma (BCC) is ill-defined.Develop a tumor (T) staging system for BCC predicting metastasis/death and compare its performance to AJCC 8th …
Preventing Complications in Dermatologic Surgery: Pre-surgical Concerns.
Cutaneous surgery has become critical to comprehensive dermatologic care, and dermatologists must therefore be equipped to manage the risks associated with surgical procedures. As complications may occur at any point …
Comorbidity screening in Hidradenitis Suppurativa: evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations.
Hidradenitis suppurativa (HS) is associated with comorbidities that contribute to poor health, impaired life quality, and mortality risk.To provide evidence-based screening recommendations for comorbidities linked to HS.Systematic reviews were performed …
Identification of clinically useful predictive genetic variants in pachyonychia congenita.
Pachyonychia congenita (PC) refers to a group of autosomal dominant disorders caused by mutations in five keratin genes (KRT16, KRT6A, KRT17, KRT6B, or KRT6C). Current disease classification is based on …
Super-high magnification dermoscopy can add information for the differential diagnosis between melanoma and atypical nevi.
Dermoscopy is the most used non-invasive imaging technique for the clinical diagnosis of melanoma (MM). Super-high magnification dermoscopy at 400x magnification (D400) has been recently developed and can reveal additional …
JAK inhibitors for atopic dermatitis: a promising treatment modality.
Atopic dermatitis (AD) is chronic, pruritic, inflammatory skin disease that affects a significant portion of the population in industrialized nations. For non-responders to conventional therapies, AD can significantly reduce sleep …
The efficacy and tolerability of tetracyclines and clindamycin plus rifampicin for the treatment of hidradenitis suppurativa; results of a prospective European cohort study.
Tetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line therapy in current Hidradenitis Suppurativa (HS) guidelines. However, evidence for their efficacy is drawn from small studies, often without …
Validity and reliability of Patient-Reported Outcomes Measurement Information System Global Health scale in adults with atopic dermatitis.
Patient-Reported Outcomes Measurement Information System Global Health (PGH) was validated to assess health-related quality of life (HRQOL) in several diseases. Little is known about its measurement properties in adult atopic …
Bromhidrosis Treatment Modalities: A Literature Review.
Treatment options for Bromhidrosis include Botulinum toxin therapy, microwave-based therapy, laser therapy, and surgerical intervention. There have been limited studies comparing their efficacies.The purpose of this literature review is to …
Small molecule inhibitors and biologics in treating nail psoriasis: a systematic review and network meta-analysis.
Various systemic immunomodulating therapies have been investigated to treat nail psoriasis, but the efficacy remains unclear.To perform a systematic review and network meta-analysis (NMA) to evaluate the efficacy of small …