Platelet-rich plasma (PRP) has shown some promise in the treatment of alopecia areata.To evaluate the effect of PRP on hair regrowth and lesional T-cell cytokine expression in alopecia areata METHODS: …
Association between vitiligo and hearing loss: A systemic review and meta-analysis.
Vitiligo is a common depigmenting disorder caused due to autoimmune destruction of melanocytes. Some evidences suggest the involvement of melanocytes in the auditory system in the disease process. However, the …
Clinicopathological analysis of primary cutaneous CD4-positive small/medium pleomorphic T-cell lymphoproliferative disorder: a retrospective study of 22 patients.
Primary cutaneous CD4-positive small/medium pleomorphic T-cell lymphoproliferative disorder has been defined as a type of lymphoproliferative disorder with indolent clinical course and excellent prognosis, yet a precise diagnosis is still …
Dowling-Degos disease: a review.
Dowling-Degos disease is a rare autosomal dominant genodermatosis. It is characterized by acquired reticulate hyperpigmentation over the flexures, comedone-like follicular papules, and pitted perioral scars that usually develop during adulthood. …
Drug interactions of natural supplements in dermatology: a review.
Limited information is available on the drug-drug interactions of natural supplements in dermatology. Many natural supplements are available over the counter, but drug-drug interactions can occur. This study reviews the …
Features of oral squamous cell carcinoma in ex vivo fluorescence confocal microscopy.
Real-time microscopic imaging of freshly excised oral squamous cell carcinomas (OSCCs) would be potentially supportive in rapid recognition of oral malignancy and an optimal and time-saving management of patients’ surgical …
Genes and phenotypes in vascular malformations.
Vascular malformations (VMs) are caused by localized defects of vascular development. Most VMs are due to sporadic, postzygotic mutations, while some are the result of autosomal dominant germline mutations. Genotype-phenotype …
Vitiligo: an update on systemic treatments.
Vitiligo is an autoimmune skin condition characterized by depigmented macules and patches, and has a huge psychosocial impact on patients. Treatment of vitiligo aims to prevent the spread of disease …
The Immunopathogenesis and Immunotherapy of Cutaneous T Cell Lymphoma: Part II, Current and Future Approaches.
In the past few decades, immunotherapy has emerged as an effective therapeutic option for patients with cutaneous T cell lymphoma (CTCL). CTCL is characterized by progressive impairment of multiple arms …
The Immunopathogenesis and Immunotherapy of Cutaneous T Cell Lymphoma: Part I, Pathways and Targets for Immune Restoration and Tumor Eradication.
Cutaneous T cell lymphomas (CTCLs) are malignancies of skin-trafficking T cells. Patients with advanced CTCL manifest immune dysfunction that predisposes to infection and suppresses the anti-tumor immune response. Therapies that …