Immune checkpoint inhibitors (ICIs)-mediated psoriasis poses significant diagnostic and therapeutic challenges.To report data on ICI-mediated psoriasis, emerging from the largest so far cohort and to propose a step-by-step management algorithm.The …
Mohs micrographic surgery for male genital tumors: Local recurrence rates and patient-reported outcomes.
Local recurrence rates (LRR) after Mohs micrographic surgery (MMS) for male genital cancers have been reported in only a few small case series, and patient-reported outcomes (PRO) have not been …
Terra firma-forme dermatosis: a systematic review.
Terra firma-forme dermatosis (TFFD) is an acquired pigmentation disorder that promptly regresses after applying isopropyl alcohol 70%. The clinical presentation ranges from patches of brownish discoloration to velvety hyperkeratotic plaques. …
A study of medication errors during the prescription stage in the pediatric critical care services of a secondary-tertiary level public hospital.
Medication Errors (MEs) are considered the most common type of error in pediatric critical care services. Moreover, the ME rate in pediatric patients is up to three times higher than …
Guidelines for the management of hidradenitis suppurativa: recommendations supported by the Centre of Evidence of the French Society of Dermatology.
Hidradenitis suppurativa (HS) is a painful chronic inflammatory skin disease which impacts quality of life substantially. Its prevalence is estimated to 0.7%.1 Various pathophysiological hypotheses exist, but no therapeutic consensus, …
News on infantile haemangioma. Part 1: clinical course and pathomechanism.
Currently, there is no doubt that the first choice of treatment for alarming infantile haemangiomas (IHs) is oral beta-blockers. However, research in this field remains active, as the pathogenesis of …
CERKL is Upregulated in Cutaneous Squamous Cell Carcinoma and Maintains Cellular Sphingolipids and Resistance to Oxidative Stress.
Ceramide Kinase-Like Protein (CERKL) was originally described in retinal tissue. CERKL has been shown to protect cells from oxidative stress, and mutations in CERKL underlie the inherited disease, retinitis pigmentosa. …
Risk factors for melanoma by anatomical site: an evaluation of aetiological heterogeneity.
Melanoma aetiology has been proposed to have two pathways – determined by naevi and type of sun exposure – and related to the anatomical site where melanoma develops.We examined associations …
Topical Corticosteroids Normalize both Skin and Systemic Inflammatory Markers in Infant Atopic Dermatitis.
Atopic dermatitis (AD) is the most common inflammatory skin disease. It is highly heterogeneous in clinical presentation, treatment response, disease trajectory and associated atopic comorbidities. Immune biomarkers are dysregulated in …
Ecthyma gangrenosum due to Pseudomonas aeruginosa sepsis as initial manifestation of X-linked agammaglobulinemia: a case report.
X-linked agammaglobulinemia (XLA, OMIM#300,300), caused by mutations in the Bruton tyrosine kinase (BTK) gene, is a rare monogenic inheritable immunodeficiency disorder. Ecthyma gangrenosum is a cutaneous lesion caused by Pseudomonas …