The effectiveness and cost-effectiveness of biologic therapies for psoriasis are significantly compromised by variable treatment responses. Thus, more precise management of psoriasis is needed.We aim to identify subgroups of psoriasis …
Development of a shared decision-making tool in vitiligo: an international study.
Shared Decision-Making tools (SDMt) are visual tools developed to promote joint medical decision-making between physician and patient. In dermatology, there is a paucity of such tools.To develop and validate a …
Mucosal Kaposi’s sarcoma in HIV-negative patients: a large case series from a single, tertiary referral center in Italy.
Mucosal involvement in HIV-negative Kaposi’s sarcoma (KS) is uncommon but has potentially serious repercussions on patient care. Evidence regarding its epidemiology and optimal management is limited. Invasive endoscopic staging at …
The risk of malignancy in secukinumab-treated psoriasis, psoriatic arthritis and ankylosing spondylitis patients: analysis of up to five-year clinical trial and post-marketing surveillance data.
Data on the use of biologic therapy and malignancy risk are inconsistent due to limited long-term robust studies.To assess the malignancy risk in secukinumab-treated psoriasis, psoriatic arthritis (PsA) and ankylosing …
Basal cell carcinoma and dermal nevi of the face: comparison of localization and dermatoscopic features.
Basal cell carcinoma (BCC) and dermal nevi located on the face can easily be confused on clinical examination. Little is known about the different preferential localizations of these entities, and …
Reconstructive options for cutaneous dorsal hand defects.
Moderate to large dorsal hand defects pose reconstructive challenges owing to the small surface area, immobile adjacent finger tissue, and thin, fragile skin.To present reconstructive options for moderate to large …
Topical preparations for the treatment of mild to moderate acne vulgaris: systematic review and network meta-analysis.
Acne is very common and can have substantial impact on wellbeing. Guidelines suggest first line management with topical treatments but there is little evidence regarding which are most effective.To identify …
Dynamic dermoscopic and reflectance confocal microscopic changes of melanocytic lesions excised during follow-up.
Digital dermoscopy follow-up (DDF) is useful in improving melanoma recognition, catching early changes over time, although benign nevi can also show changes. Reflectance confocal microscopy (RCM) improves melanoma diagnostic accuracy …
Guidelines of care for the management of actinic keratosis.
Actinic keratoses (AK) are rough scaly patches that arise on chronically ultraviolet-exposed skin and can progress to keratinocyte carcinoma.This analysis examined the literature related to the management of AK to …
Epidemiology and risk factors for the development of cutaneous toxicities in patients treated with immune checkpoint inhibitors: A United States population-level analysis.
A variety of dermatoses have been reported in the growing number of patients treated with immune checkpoint inhibitors (ICIs), but the current understanding of cutaneous immune related adverse events (irAEs) …