Poikiloderma is a skin condition that combines atrophy, telangiectasia, and macular pigment changes (hypo- as well as hyperpigmentation). It is often mistaken for mottled pigmentation by general practitioners or nondermatology …
The cardiovascular safety of oral alitretinoin. A population-based cohort study involving 19,513 patients exposed to oral alitretinoin.
Oral alitretinoin is a retinoid used for severe chronic hand eczema. Although caution is recommended for patients with uncontrolled dyslipidaemia or cardiovascular risk factors, the actual atherothrombotic risk has not …
Effect of Dermatologic Consultation on Survival in Patients with Checkpoint Inhibitor Associated Cutaneous Toxicity.
Cutaneous immune-related adverse events (cirAEs) are a common side effect of immune checkpoint inhibitors. However, prior work examining these toxicities in detail has considered only the fraction of events evaluated …
Host traits, lifestyle and environment are associated with the human skin bacteria.
The human skin offers diverse ecosystems for microbial symbionts. However, the factors shaping skin-microbiome interactions are still insufficiently characterized. This contrasts to the broader knowledge about the factors influencing the …
Inflammatory Skin Diseases and the Risk of Chronic Kidney Disease – Population-Based Case-control and Cohort analyses.
Emerging evidence suggests an association between common inflammatory skin diseases and chronic kidney disease (CKD).To explore the association between CKD stages 3-5 and atopic eczema, psoriasis, rosacea, and hidradenitis suppurativa.We …
Oral mini-pulse therapy in vitiligo: a systematic review.
There is limited evidence supporting the use of alternative treatments for patients with nonstable vitiligo.This study aimed to review the effects of oral mini-pulse (OMP) therapy in the management of …
Psychiatric Disorders and Suicidal Behavior in Patients with Acne Prescribed Oral Antibiotics versus Isotretinoin: Analysis of a Large Commercial Insurance Claims Database.
The association between isotretinoin and psychiatric disturbance, including depression and suicidal behavior, is controversial.To investigate whether acne patients prescribed isotretinoin or antibiotics were more likely to have psychiatric disorders and/or …
Retrospective analysis of adverse events with dupilumab reported to the United States Food and Drug Administration.
Atopic dermatitis (AD) is one of the most common inflammatory skin diseases and has aesthetic, physical, and emotional-social sequelae when left untreated.To classify the most common adverse reactions associated with …
The increasing problem of treatment-resistant fungal infections: a call for antifungal stewardship programs.
Antimicrobial stewardship (AMS) programs have been widely recognized among the public health community. These programs focus majorly on bacterial infections, efficient antibiotic use, and measures to curb increasing antibacterial resistance. …
Circulating long noncoding RNA growth arrest-specific transcript 5 as a diagnostic marker and indicator of degree of severity in plaque psoriasis.
The current study aims at evaluating the role of circulating or cell-free long noncoding ribonucleic acid (lncRNA) growth arrest-specific 5 (GAS5) in plaque psoriasis and at investigating its relationship with …