Because several nail disorders share similar clinical features, their diagnosis and management can be challenging to clinicians. The physical examination may disclose localized abnormalities or point to an underlying systemic …
Cutaneous mesenchymal tumors treated with Mohs micrographic surgery: a comprehensive review.
Cutaneous mesenchymal tumors (CMT) are rare tumors with wide clinicopathologic heterogeneity. Treatment of malignant cutaneous mesenchymal tumors traditionally includes wide local excision (WLE), though Mohs micrographic surgery (MMS) has been …
Expression of hedgehog signaling molecules in microcystic adnexal carcinoma.
Microcystic adnexal carcinoma (MAC) is a rare skin neoplasm that has not been characterized on a molecular basis.We aimed to assess expression profiles of hedgehog (HH) signaling molecules in MAC …
Sexual function is adversely affected in the majority of men presenting with penile lichen sclerosus.
Male genital lichen sclerosus (MGLS) is a chronic inflammatory condition which can present with a range of debilitating symptoms. Sexual dysfunction is reported by most women with lichen sclerosus but …
United Kingdom Psychodermatology Services in 2019: service provision has improved but is still very poor nationally.
Psychodermatology is an emerging sub-specialty of dermatology. Psychodermatology clinics use a multidisciplinary approach to deal with psychological or psychiatric elements related to skin disease. Two previous studies in 2004 and …
Azathioprine hypersensitivity syndrome. Report of two cases with cutaneous manifestations.
Azathioprine is an immunosuppressant drug used in many dermatological and non-dermatological pathologies. Azathioprine hypersensitivity syndrome is a rare idiosyncratic reaction no related to dose or thiopurine methyltransferase activity. Up to …
Correlation of anti-γ/ε nicotinic acetylcholine receptor antibody levels with anti-desmoglein 1,3 antibody levels and disease severity in pemphigus vulgaris.
The role of non-desmoglein (Dsg) antigens in pemphigus vulgaris (PV) pathogenesis have been suggested in several studies. Acetylcholine receptors (AchR), are one of the most important groups of these antigens. …
Skin biopsy as an aid to diagnosis of disorders of the nervous system without cutaneous manifestations.
There are several neurological diseases wherein skin biopsy is useful for diagnosis, even in the absence of skin involvement. Skin biopsy is especially relevant in diseases in which the metabolic …
Allergic contact dermatitis: a significant environmental and occupational skin disease.
This review article seeks to provide an overview of allergic contact dermatitis (ACD) as a significant environmental and occupational skin disease, the phases of ACD, its causes from the occupational …
Body Site Distribution of Pediatric-Onset Morphea and Association with Extracutaneous Manifestations.
The distribution of pediatric-onset morphea and site-based likelihood for extracutaneous complications has not been well-characterized.Characterize lesional distribution of pediatric-onset morphea and determine sites with the highest association with extracutaneous manifestations.A …