To evaluate the clinical efficacy of tetracycline, doxycycline, and lymecycline in patients with hidradenitis suppurativa (HS).A prospective study of three different treatment regimens in patients with HS; oral tetracycline 500 mg …
Predicting sentinel node positivity in melanoma patients: external validation of a risk-prediction calculator (the MIA nomogram) using a large European population-based patient cohort.
A nomogram to predict SN-positivity (the Melanoma Institute Australia (MIA) nomogram) was recently developed and externally validated using two large single-institution databases. However, there remains a need to further validate …
Supportive care in the acute phase of Stevens-Johnson syndrome and toxic epidermal necrolysis: an international, multidisciplinary DELPHI-based consensus.
Supportive care is the cornerstone of adult and pediatric management of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, consensus on the modalities of supportive care is lacking.Our aim …
Dupilumab treatment in atopic dermatitis patients in the Netherlands versus Japan: a comparative cohort study revealing a discrepancy in patient-reported outcome measures.
Dupilumab was equally effective among all racial subgroups in clinical trials, but a direct comparison in daily practice is lacking.To investigate effectiveness of dupilumab in atopic dermatitis (AD) patients in …
Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort.
Atopic dermatitis (AD) disease activity and severity is highly variable during childhood. Early attempts to identify subtypes based on disease trajectory have assessed AD presence over time without incorporating severity.To …
Oral dimethyl fumarate induces changes within the peripheral neutrophil compartment of psoriasis patients that are linked with skin improvement.
Dimethyl fumarate (DMF) is a treatment for moderate-to-severe psoriasis and multiple sclerosis. DMF therapy typically improves skin inflammation within the first 3 months of treatment. DMF is a prodrug that …
Balloon cell melanoma: a systematic review.
Balloon cell melanoma (BCM) is a rare presentation of malignant melanoma characterized by large, foamy melanocytes lacking pigmentation. This is a comprehensive review of the clinical, dermoscopic, and histological features …
Deodorants and antiperspirants: identification of new strategies and perspectives to prevent and control malodor and sweat of the body.
Excessive sweating and body odors in many cultures can cause negative perceptions of an individual and in many cases is related to poor hygiene. Personal hygiene products have been developed …
Visible Light Part I. Properties and Cutaneous Effects of Visible Light.
Approximately fifty percent of sunlight reaching the Earth’s surface is visible light (400-700 nm). Other sources of visible light include lasers, light-emitting diodes (LEDs), and flash lamps. Photons from visible …
Visible Light Part II. Photoprotection against visible and ultraviolet light.
Cutaneous photobiology studies have focused primarily on the UV portion of the solar spectrum. However, VL comprises 50% of EMR that reaches the earth’s surface, and, as discussed in Part …