Hidradenitis suppurativa (HS) is a chronic inflammatory follicular disorder that involves painful nodules, abscesses, and tunnels of intertriginous sites. Although the etiology has not been fully elucidated, recent studies have …
Hydroxychloroquine-induced acute generalized exanthematous pustulosis: a series of seven patients and review of the literature.
Hydroxychloroquine (HCQ)-induced acute generalized exanthematous pustulosis (AGEP) is poorly described in the literature. The aim of our study was to characterize the clinical, laboratory, allergological, and genetic features of HCQ-induced …
The differential expression of EPHB4 and ephrin B2 in cutaneous squamous cell carcinoma according to the grade of tumor differentiation: a clinicopathological study.
EPHB4 and its ligand, ephrin B2, which are receptor tyrosine kinases of the erythropoietin-producing hepatocellular (EPH) family, are known to be linked to several human cancers. The aim of this …
Baricitinib in patients with moderate-to-severe atopic dermatitis: Results from a randomized monotherapy Phase 3 trial in the United States and Canada (BREEZE-AD5).
Baricitinib, an oral, selective Janus kinase (JAK)1/JAK2 inhibitor, is being studied for moderate-to-severe atopic dermatitis (AD) in adults.To evaluate the efficacy and safety of baricitinib monotherapy in a North American …
Discoid lupus erythematosus solely involving the eyelids: case report and literature review.
The involvement of eyelids occurs in only 5-6% of patients with discoid lupus erythematosus (DLE), commonly with mucocutaneous lesions elsewhere. DLE solely involving the eyelids is relatively rare. This study …
Phacomatosis spilosebacea: A new name for a distinctive binary genodermatosis.
Phacomatosis pigmentokeratotica (PPK) is defined by the association of papular nevus spilus arranged in a flag-like pattern and sebaceous nevus following Blaschko’s lines. A systematic search of the worldwide literature retrieved …
Slack as a virtual undergraduate dermatology community: a pilot.
Dermatology is recognised as under-represented in UK undergraduate curricula. With a diagnostic and educational toolkit that is heavily centred on face-to-face clinical examination, dermatology education has been disproportionately affected by …
Dermoscopy and reflectance confocal microscopy of balloon cell nevi: a series of 10 cases.
Balloon cell nevus (BCN) is a rare histopathological entity. It is usually represented by an asymptomatic brown smooth or polypoid lesion, but no clinical features allow differentiation from other melanocytic …
Investigating the presence of neutrophil extracellular traps in septal and lobular cutaneous panniculitides.
Panniculitides are a heterogeneous group of inflammatory dermatoses involving the subcutaneous fatty tissue. Histologically, they are classified into septal and lobular panniculitis, according to the predominant localization of the inflammatory …
Contact dermatitis associated with preservatives: Retrospective analysis of North American Contact Dermatitis Group data, 1994 through 2016.
Preservatives are often necessary components of commercial products. Large-scale North American studies on preservative allergy are limited.To evaluate demographics, positive patch test reactions (PPTRs), clinical relevance, and trends for preservatives tested …