Several countries have introduced transparency databases since the last assessment of conflicts of interest (COIs) in dermatology randomised controlled trials (RCTs) in 2004. We assessed the prevalence of financial COIs …
Downregulation of SHANK-associated RH domain-interacting protein elevates interleukin-33 expression by stimulating the Janus kinase 2/signal transducer and activator of transcription signaling pathway in HaCaT cells.
Atopic dermatitis (AD) is a chronic inflammatory skin disease in which T-helper type 2 (Th2 ) immune responses are dominant. SHANK-associated RH domain interacting protein (SHARPIN) is expressed at low levels …
Drug survival of Adalimumab and Infliximab in Hidradenitis Suppurativa Patients: A Daily Practice Cohort Study.
Biologics are often required for treatment of hidradenitis suppurativa (HS). However, data on the drug survival of biologics in daily practice are currently lacking.To assess the drug survival of anti-TNF …
Five-year efficacy and safety of tildrakizumab in patients with moderate to severe psoriasis who respond at week 28: pooled analyses of two randomised phase 3 clinical trials (reSURFACE 1 and reSURFACE 2).
The phase 3 reSURFACE 1 and reSURFACE 2 (NCT01722331/NCT01729754) trials of the anti-interleukin-23p19 monoclonal antibody tildrakizumab for psoriasis treatment are complete.We present 5-year pooled data from reSURFACE 1 and reSURFACE …
Somatostatin receptors: an alternative treatment target for advanced Merkel cell carcinoma.
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high risk of returning and spreading. It affects about 2500 new patients every year in the USA. …
Psoriasis: The Skin I’m In – Development of a behaviour change tool to improve the care and lives of people with psoriasis.
Psoriasis is a long-term skin condition associated with considerable life impairment. Extensive literature regarding the needs of patients with psoriasis is not translated into clinical practice.To explore and communicate the …
Xeroderma pigmentosum in Yemen.
The incidence of xeroderma pigmentosum (XP) in Yemen seems to be quite high but there are no previous reports.To study the clinicoepidemiologic aspect of XP in Yemen.All 40 patients (24 …
News on infantile haemangioma. Part 2: therapy and evaluation.
Infantile haemangioma (IH) is the most frequently occurring tumour of childhood. While benign, in more than half of the cases, less or more severe sequelae can be observed. In Part …
Dermoscopy in general dermatology (non-neoplastic dermatoses): pitfalls and tips.
Dermoscopy is gaining appreciation in the spectrum of non-neoplastic skin conditions, especially papulosquamous and granulomatous dermatoses. However, the use of dermoscopy in such diseases has not yet acquired a standard …
The role of prostaglandins in androgenetic alopecia.
Though androgenetic alopecia (AGA) is one of the most common diseases affecting both sexes and all races, its pathogenesis is not completely clarified. The aim of this study was to …