Basal cell carcinoma (BCC) is the commonest cancer affecting white-skinned individuals, and worldwide incidence is increasing. Although rarely fatal, BCC is associated with significant morbidity and costs.To assess the effects …
Clinical Photography in Skin of Color: Tips and Best Practices.
High quality photos are critical to dermatology: both for clinical care and education. Although best practices for capturing skin photos have been outlined,1 these omit specific challenges of taking photos …
A 1% glycopyrronium bromide cream for the topical treatment of primary axillary hyperhidrosis: Efficacy and Safety Results from a Phase 3a Randomised Controlled Study.
Effective topical treatment options for patients with primary axillary hyperhidrosis are limited. Recent phase 1 trial showed promising results regarding efficacy and safety for topical cream containing glycopyrronium bromide (GPB).To …
What is the demand for out-of-hours dermatology? A UK based region-wide survey of dermatology demand and provision during the evenings and at weekends.
There is wide variation both locally and nationally with respect to the provision of out-of-hours dermatology. Few centres now offer a 24 hour a day service 7 days per week1,2 …
Facial and neck erythema associated with dupilumab treatment: A systematic review.
Dupilumab-associated facial and/or neck erythema was not reported in phase 3 clinical trials for the treatment of atopic dermatitis, but there have been a number of reports of patients developing …
Trim21 promotes inflammation in keratinocytes of psoriatic patients.
Psoriasis is a skin disease that manifests as itchy, scaly plaques (patches) on the skin. It is associated with both a physical and psychological burden, and affects 0.5-1% of children …
Cannabinoids in Dermatologic Surgery.
Though known as a medicinal herb for centuries, the recent legalization of cannabinoids across many states has ushered in a new era where cannabinoids have become a popular treatment option …
Biologic Treatment Outcomes in Mucous Membrane Pemphigoid: A Systematic Review.
Mucous membrane pemphigoid (MMP) is an autoimmune disease, which can lead to fibrosis of mucous membranes and functional impairment. Biologic agents should be explored as alternative treatment options to improve …
Differential Profiles of Gamma-Secretase-Notch Signaling in Hidradenitis Suppurativa: The Need for Genotype-Endotype-Phenotype Analysis.
Hidradenitis Suppurativa (HS) is a chronic inflammatory dermatosis in which a subset of patients display genetic variants in components of the gamma secretase complex1 proposed to result in dysregulation of …
Classification of lower extremity venous malformations and risk of knee involvement: A retrospective cohort study.
Venous malformations (VM) are the most common vascular anomaly in the lower extremity. VM can be classified as focal, multifocal or diffuse types. Intraarticular VM (IA-VM) of the knee portends …