Local recurrence rates (LRR) after Mohs micrographic surgery (MMS) for male genital cancers have been reported in only a few small case series, and patient-reported outcomes (PRO) have not been …
Terra firma-forme dermatosis: a systematic review.
Terra firma-forme dermatosis (TFFD) is an acquired pigmentation disorder that promptly regresses after applying isopropyl alcohol 70%. The clinical presentation ranges from patches of brownish discoloration to velvety hyperkeratotic plaques. …
Guidelines for the management of hidradenitis suppurativa: recommendations supported by the Centre of Evidence of the French Society of Dermatology.
Hidradenitis suppurativa (HS) is a painful chronic inflammatory skin disease which impacts quality of life substantially. Its prevalence is estimated to 0.7%.1 Various pathophysiological hypotheses exist, but no therapeutic consensus, …
News on infantile haemangioma. Part 1: clinical course and pathomechanism.
Currently, there is no doubt that the first choice of treatment for alarming infantile haemangiomas (IHs) is oral beta-blockers. However, research in this field remains active, as the pathogenesis of …
CERKL is Upregulated in Cutaneous Squamous Cell Carcinoma and Maintains Cellular Sphingolipids and Resistance to Oxidative Stress.
Ceramide Kinase-Like Protein (CERKL) was originally described in retinal tissue. CERKL has been shown to protect cells from oxidative stress, and mutations in CERKL underlie the inherited disease, retinitis pigmentosa. …
Risk factors for melanoma by anatomical site: an evaluation of aetiological heterogeneity.
Melanoma aetiology has been proposed to have two pathways – determined by naevi and type of sun exposure – and related to the anatomical site where melanoma develops.We examined associations …
Topical Corticosteroids Normalize both Skin and Systemic Inflammatory Markers in Infant Atopic Dermatitis.
Atopic dermatitis (AD) is the most common inflammatory skin disease. It is highly heterogeneous in clinical presentation, treatment response, disease trajectory and associated atopic comorbidities. Immune biomarkers are dysregulated in …
CCL20 in Psoriasis: A Potential Biomarker of Disease Severity, Inflammation, and Impaired Vascular Health.
Psoriasis is associated with increased cardiovascular risk that is not captured by traditional pro-inflammatory biomarkers.To investigate the relationship between psoriasis area and severity index (PASI), circulating pro-inflammatory biomarkers, and vascular …
Relationship Between Body Mass Index and Atopic Dermatitis: Critical Appraisal of a Mendelian Randomization Approach in Exploring Causality.
Atopic dermatitis (AD) is a common, chronic inflammatory skin disease with a complex etiology including genetic and environmental risk factors.1 Obesity has been associated with increased AD risk and severity,2 …
Hand Dermatitis in Adults Referred for Patch Testing: Analysis of North American Contact Dermatitis Group Data, 2000-2016.
Hand eczema (HE) is a heterogeneous and burdensome disorder.To characterize the clinical characteristics, etiologies and allergen relevance in adults with HE referred for patch testing.Retrospective analysis (2000-2016) of North American …