Drug survival rates reflect efficacy and safety and may be influenced by the availability of alternative treatment options. Little is known about time-dependent drug survival in psoriasis and the effect …
Narrow resection margins are not associated with mortality or recurrence in patients with Merkel cell carcinoma: a retrospective study.
Wide local excision constitutes the standard of care for Merkel cell carcinoma, but the optimal margin width remains controversial.To assess whether narrow margins (0.5 – 1 cm) were associated with …
Merkel Cell Carcinoma.
Merkel cell carcinoma (MCC) of the skin is a rare, aggressive form of skin cancer which metastasises to other parts of the body. This cutaneous neuroendocrine tumour mainly affects older …
Differences between Stevens-Johnson syndrome versus toxic epidermal necrolysis.
To retrospectively review the outcomes of two rare cutaneous diseases, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), and to question the practice of averaging the mortality rate on the …
Prevalence of scratching during examination among patients with scabies and among patients with other pruritic dermatoses.
Scabies is a parasitic skin disease. Its clinical diagnosis may be challenging.In a prospective observational study, we enrolled all consecutive patients ≥16 years of age with a presumptive diagnosis of scabies …
Cutaneous tuberculosis of the pinna.
Cutaneous tuberculosis (CTB) rarely involves the ear as the primary site, but while diagnosing and treating ear infections, it should be considered a differential diagnosis in a tropical country such …
Bidirectional Association between Atopic Dermatitis, Conjunctivitis and other Ocular Surface Diseases: A Systemic Review and Meta-Analysis.
Conjunctivitis and several other ocular surface diseases (OSDs) have been linked to atopic dermatitis (AD) and its treatment.To examine the association between AD, conjunctivitis and other OSDs.A systematic review and …
Incidence of psoriasis among adults in the United States: A sex- and age-adjusted population analysis.
Information on recent trends in overall and subgroup incidences in psoriasis is limited.To estimate current incidence of psoriasis in the U.S., compare incidences among demographic subgroups, and evaluate recent disease …
Five-Year Survival in Patients with Nodular and Superficial Spreading Melanomas in the US Population.
While superficial spreading melanomas (SSM) are diagnosed as thinner lesions, nodular melanomas (NM) have a more rapid growth rate and are biologically more aggressive compared to other histologic subtypes.To determine …
Long-term efficacy and safety of ixekizumab: 5-year analysis of the UNCOVER-3 randomized controlled trial.
To report efficacy and safety of the approved IXE dose over 5 years from UNCOVER-3. (NCT01646177).Patients (N=1346) were randomized 1:2:2:2 to receive subcutaneous injections of placebo, etanercept 50 mg twice …