Silicone adhesive multilayer foam dressings are used as adjuvant therapy to prevent hospital-acquired pressure ulcers (PUs).Determine if silicone foam dressings in addition to standard prevention reduce PU incidence category 2 …
Incidence of acute complications of herpes zoster among immunocompetent adults in England: a matched cohort study using routine health data.
Herpes zoster can cause rare but serious complications; the frequency of these complications has not been well-described.We aimed to quantify the risks of acute non-postherpetic neuralgia (PHN) zoster complications, to …
Skin sensitisation to fragrance hydroperoxides: interplay between dendritic cells, keratinocytes and free radicals.
Skin sensitisation to hydroperoxides (R-OOHs) of the commonly used fragrance terpenes limonene, linalool and citronellol is frequently reported. R-OOHs are believed to initiate the process leading to sensitisation and allergic …
Evaluation of Dermatological Life Quality Index, Sexual Dysfunction, and Other Psychiatric Diseases in Patients Diagnosed with Vitiligo with and without Genital Involvement.
Because skin lesions affect self-image, vitiligo affects an individual’s emotional and psychological well-being, sexual life, and relationships with other people. The literature contains a limited number of studies regarding the …
Pyridoxine for prevention of hand-foot syndrome caused by chemotherapy agents: a meta-analysis.
Hand-foot syndrome (HFS) is a common systemic skin toxicity syndrome caused by chemotherapy agents. However, there is no uniform clinical treatment for HFS. It is reported that pyridoxine (vitamin B6) …
Molecular epidemiology of pachyonychia congenita in the Israeli population.
Pachyonychia congenita (PC) is a rare autosomal dominant disorder featuring palmoplantar keratoderma, nail dystrophy, oral leukokeratosis, pilosebaceous cysts and natal teeth. PC results from dominant mutations in one of five …
Clinical characteristics and histopathological changes of morphea: A single-center, retrospective study of 137 patients.
The clinicopathologic correlations and prognostic risk factors for refractory disease in morphea (localized scleroderma) are poorly described.To investigate the association between clinical characteristics and histopathological features of morphea and identify …
Recommended core outcome instruments for health-related quality of life, long-term control and itch intensity in atopic eczema trials: results of the HOME VII consensus meeting.
The Harmonising Outcome Measures for Eczema (HOME) initiative has established a core outcome set of domains for atopic eczema clinical trials. Previous consensus meetings have agreed upon preferred instruments for …
Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial: a critical appraisal.
Vitiligo is an acquired condition which presents as cutaneous depigmentation. There is no licensed treatment for the re-pigmentation of vitiligo lesions, however, several therapies are used routinely and have been …
Scoping the international impact from four independent national dermatology trials.
Research impact describes whether and how research results in wider benefits to society beyond academic publication. Little is known about translation of clinical trial research into dermatological practice .We scoped …