Bloodroot (Sanguinaria canadensis) is a plant, native to North America, containing bioactive compounds that interrupt biological processes. It has been around for centuries and is known for its medicinal properties. …
Laugier-Hunziker syndrome: a case report of the pediatric patient and review of the literature.
Laugier-Hunziker syndrome (LHS) is a rare, idiopathic pigmentary disorder especially affecting the lips and oral mucosa. At present, no more than 200 cases of patients diagnosed with LHS syndrome have …
Acquired ungual fibrokeratoma: a systematic review of the literature.
Acquired ungual fibrokeratomas (AUFKs) are benign recurrent fibrokeratotic tumors of the nail unit of uncertain etiology. Little is known about the optimal modality to successfully treat these lesions. No systematic …
Quality Assurance and Characterisation of NB-UVB Devices for use at home – Lessons from the Hi-Light Vitiligo Trial.
Hand-held narrowband UVB (NB-UVB) devices are available for the treatment of various skin conditions, but their optical radiation omissions are often not thoroughly characterised. Following a pilot study1 that identified …
Real-world effectiveness and tolerability of dupilumab in adult atopic dermatitis: A single centre, prospective one-year observational cohort study of the first 100 patients treated.
Dupilumab (Dupixent®) is the first biologic drug licensed for treatment of adults with atopic dermatitis (AD). Data regarding its long-term real-world effectiveness and tolerability are limited. We report comprehensive outcome …
Topical corticosteroid vehicle composition and implications for clinical practice.
This narrative review highlights the therapeutic significance of topical corticosteroid (TCS) vehicles and provides subsequent guidance to improve clinical and research outcomes. A greater understanding of the relationship between the …
Integrating neuronal involvement into the immune and genetic paradigm of vitiligo.
In this review we show how the neuronal theory is relevant to the convergence theory for the mechanism causing vitiligo, especially the segmental type. Neuropetides and neurotransmitters, e.g. neuropeptide-Y and …
Trends in Mortality and Cause-specific Mortality among patients with Psoriasis and Psoriatic Arthritis in Ontario, Canada.
There is limited information about mortality rates among patients with psoriasis and psoriatic arthritis (PsA) in North America and their change over the past two decades.To compare all-cause and cause-specific …
Clinical size is a poor predictor of invasion in melanoma of the lentigo maligna type.
There are no well-defined clinical factors to predict the risk of occult invasion in melanoma of the lentigo maligna type (LM) prior to complete histopathologic analysis.To evaluate whether clinical size …
“Fake news” in dermatology. Results from an observational, cross-sectional study.
Social networks have become a means for disseminating information on health-related matters.Describe the characteristics and analyze the accuracy of the dermatology content that is most often shared on the most …