Pemphigus is an autoimmune intraepidermal bullous disease which can affect skin and∕or mucous membranes. Trichoscopy is a non-invasive tool that can help in the clinical diagnosis especially if the patient …
Association of Psoriasis with Colorectal Cancer: A Systematic Review and Meta-Analysis.
The relation between psoriasis and colorectal cancer (CRC) was largely unclear.To investigate the association of psoriasis with CRC.A systematic review and meta-analysis of observational studies that examined the association of …
Low Utility of Radiological Imaging in Evaluating Cutaneous Small-Vessel Vasculitis: A Multi-institutional Retrospective Study.
Small vessel vasculitis (SVV) is a heterogenous disease which may be skin-limited, or manifestation of systemic disease. Radiological studies are often recommended in textbooks, although no data exist to define …
Systematic Review of Mohs Micrographic Surgery in Children: Identifying Challenges and Practical Considerations for Successful Application.
Few data exist to guide the application of Mohs micrographic surgery (MMS) in the pediatric population.To summarize the clinical characteristics of children undergoing MMS, identify challenges that limit the use …
Occupational Dermatitis to Facial Personal Protective Equipment in Healthcare Workers: A Systematic Review.
Prolonged wear of facial protective equipment can lead to occupational dermatoses.To identify important causes of occupational dermatoses from facial protective equipment.A systematic review following PRISMA guidelines was performed using PubMed …
Cutaneous toxicities in melanoma patients receiving checkpoint inhibitor therapy, a retrospective review: The experience of a single large specialist institution.
CPI was approved by the European Medicines Agency (EMA) in 2012 for advanced melanoma and extended to include adjuvant melanoma treatment in 2018. Expectation for survival in advanced melanoma now …
Tacrolimus 0.1% versus ciclopiroxolamine 1% for maintenance therapy in patients with severe facial seborrheic dermatitis a multicenter, double-blind, randomized controlled study.
Capsule summary Despite the absence of robust evidence, tacrolimus is quite commonly used off label as maintenance treatment for seborrheic dermatitis, in clinical practice. Tacrolimus 0.1% ointment applied twice a …
Topical anti-microbial peptide omiganan recovers cutaneous dysbiosis but does not improve clinical symptoms in patients with mild-to-moderate atopic dermatitis in a phase 2 randomized controlled trial.
Dysbiosis and colonization with Staphylococcus aureus is considered to play an important role in the pathogenesis of atopic dermatitis (AD). Recovering this dysbiosis may improve AD symptoms. Omiganan is a …
Comparison of efficacy of noncultured hair follicle cell suspension and noncultured epidermal cell suspension in repigmentation of leukotrichia and skin patch in vitiligo: a randomized trial.
Vitiligo manifests as hypo- to de-pigmented macules, which are sometimes associated with leukotrichia. For complete cosmetic improvement, the repigmentation of leukotrichia is an important component.This randomized controlled trial included patients …
Dupilumab treatment ameliorates clinical and hematological symptoms, including blood eosinophilia, in patients with atopic dermatitis.
Atopic dermatitis (AD) is an allergic disease that affects individuals of various ages. Recently, the IL-4/13 inhibitor dupilumab has gained regulatory approval for clinical use in AD patients. Dupilumab has …