Primary cutaneous lymphomas comprise a heterogeneous group of B and T cell malignancies which often show an indolent course, but can progress to aggressive disease in a subset of patients. …
Drug survival and predictor factors for discontinuation of methotrexate in psoriasis: a real-life multicenter study.
Drug survival is useful to evaluate long-term drug performance in daily practice. The aim of this study was to evaluate drug survival for methotrexate (MTX) monotherapy in patients with plaque-type …
Forewarned is Forearmed: chronic spontaneous urticaria as a potential risk to effective SARS-COV-2 vaccine uptake and global public health.
Chronic spontaneous urticaria and angioedema (CSU/A) is a common condition with an estimated global point prevalence of 0.7% (95% C.I, 0.2-1.4)(1), higher in non-White populations. Symptoms present as an ‘allergy …
Anatomical distribution of basal cell carcinoma in Israel using relative tumor density scores.
Ultraviolet radiation (UVR) is considered a major risk factor for the development of basal cell carcinoma (BCC). Calculating the relative tumor density (RTD) by adjusting the proportion of BCC lesions …
Association between long noncoding RNA taurine-upregulated gene 1 and microRNA-377 in vitiligo.
Taurine-upregulated gene 1 (TUG1) is one of the long noncoding RNAs (lncRNAs) that plays a role in melanogenesis. MicroRNA-377 (miRNA-377) is a conserved noncoding RNA that regulates angiogenesis and promotes …
IFN-α and TNF-α serum levels and their association with disease severity in Egyptian children and adults with alopecia areata.
Alopecia areata (AA) is an autoimmune skin disease characterized by abnormal levels of several cytokines, such as interferon alpha (IFN-α) and tumor necrosis factor-alpha (TNF-α), which are T-helper type 1 …
Sublingual tofacitinib for alopecia areata: a roll-over pilot clinical trial and analysis of pharmacokinetics.
Tofacitinib is a JAK1/3 inhibitor used off-label to treat alopecia areata (AA). Oral tofacitinib undergoes extensive hepatic metabolism and has numerous drug interactions and a half-life of 3 hours necessitating twice …
Hepatitis B and C among patients with hidradenitis suppurativa: a population-based study.
Hidradenitis suppurativa (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections.This retrospective cross-sectional study from 1999 to 2015 used the database of Clalit Health Services, the …
Are we born and do we die without nevi? A cross-sectional study.
It is well known that the number of nevi varies with age. However, there are a few data in the literature concerning total nevus count at different ages. The aim …
Differential diagnosis and management of hyperpigmentation.
There is an increasing recognition of ethnic dermatology to reflect the rising skin of colour (SOC) population. Hyperpigmentary disorder is one of the commonest skin concerns in SOC but there …