Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized by intense pruritus, but information on patient experience and impact on quality of life (QoL) remains understudied.To characterize disease characteristics …
Comorbidities, Mortality and Survival in Patients with Pyoderma Gangrenosum: A Danish Nationwide Registry-Nested Case-Control Study.
Pyoderma gangrenosum (PG) is an ulcerative skin disease associated with comorbidities and increased mortality. However, the literature on this topic is scarce.To investigate the mortality, prevalence and risk of comorbidities …
Paternal and maternal use of dupilumab in patients with atopic dermatitis: a case series.
Dupilumab is a relatively new treatment option for patients with moderate-to-severe atopic dermatitis. There is a lack of knowledge about treatment with dupilumab during conception in both males and females, …
International registry of dermatological manifestations secondary to COVID-19 infection in 347 Hispanic patients from 25 countries.
The infection by coronavirus disease 2019 (COVID-19) has been associated with multiple cutaneous manifestations, although characterization of them in Hispanic patients with darker skin phototypes is lacking. The objective of …
A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans.
Genome-wide association studies (GWAS) have identified genes influencing skin ageing and mole count in Europeans but little is known about the relevance of these (or other genes) in non-Europeans.To conduct …
Domains and outcomes of the core outcome set of congenital melanocytic naevi for clinical practice and research, part 2 (the OCOMEN project).
Congenital melanocytic naevi (CMN) can have a great impact on patients’ lives due to perceived stigmatization and the risk of melanoma development and neurological complications. Development of a core outcome …
Evaluation of plasma and urinary levels of vascular endothelial growth factor and matrix metalloproteinase-9 in patients with infantile hemangioma.
The pathogenesis of infantile hemangioma (IH) is not fully understood. It has been suggested that angiogenic factors increase in the proliferative stage, decreasing subsequently in the regression phase.To evaluate vascular …
Systematic Review and Meta-Analysis of Local Recurrence Rates of Head and Neck Cutaneous Melanomas after Wide Local Excision, Mohs Micrographic Surgery, or Staged Excision.
Prospective trials have not compared local recurrence rates for different excision techniques for cutaneous melanomas on the head and neck.To determine local recurrence rates of cutaneous head and neck melanoma …
Views on Mobile Health Apps for Skin Cancer Screening in the General Population: An In-Depth Qualitative Exploration of Perceived Barriers and Facilitators.
Mobile health (mHealth) applications (apps) integrated with artificial Intelligence (AI) for skin cancer screening are increasingly reimbursed by health insurers. However, an in-depth exploration of the general public’s views towards …
Efficacy and Safety of Ruxolitinib Cream for the Treatment of Atopic Dermatitis: Results From Two Phase 3, Randomized, Double-Blind Studies.
Ruxolitinib (RUX) cream demonstrated potent anti-inflammatory and antipruritic efficacy in a phase 2 study in adults with atopic dermatitis (AD).To evaluate 8-week efficacy and safety in two phase 3 studies …