Systemic photoprotection aims to negate the negative effects of ultraviolet radiation-induced DNA damage. Systemic supplements might be used as a monotherapy or in combination with topical sunscreens. Using the keywords …
Study of melanocyte density and epidermal thickness in vulvar lichen sclerosus lesions.
This study aimed to analyze changes in melanocyte density and epidermal thickness in vulvar lichen sclerosus (VLS).Vulvar skin tissues were collected from 15 VLS female patients in Beijing Hospital, classified …
Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial.
The antimelanogenesis effect of topical and oral glutathione has been shown in several in vitro and clinical studies. However, whether combination of topical and oral glutathione is superior to topical …
Limitations in the Literature Regarding Mohs Surgery and Staged Excision for Melanoma: A Critical Review of Quality and Data Reporting.
The literature supporting Mohs micrographic surgery (MMS) and staged excision (SE) in treating primary cutaneous melanoma is growing but has not been critically reviewed for bias.Articles concerning MMS/SE for melanoma …
Do we need skin toxicity? Association of immune checkpoint inhibitor and tyrosine kinase inhibitor-related cutaneous adverse events with outcomes in metastatic renal cell carcinoma.
Skin toxicity is a common, expected side effect of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) used for metastatic renal cell carcinoma (mRCC). We evaluated the association between …
Discriminating ‘DRESS minor’ from ‘DRESS major’: facial oedema aligns to the severe phenotype.
DRESS is a cutaneous and systemic drug allergy disorder. Patients exist on a severity spectrum with some developing a mild form of the disorder which fails to meet the RegiSCAR …
Clinical experience and psychometric properties of the Cardiff Acne Disability Index (CADI).
The Cardiff Acne Disability Index (CADI) is a questionnaire designed to measure the quality of life (QoL) of teenagers and young adults with acne. It has been used clinically and …
Sleep disturbance in adult dermatological patients: A cross-sectional study on prevalence, burden and associated factors.
Sleep disturbance remains insufficiently characterized in many dermatoses.To investigate the prevalence, burden and factors associated with sleep disturbance in dermatological patients.We recruited 800 patients and recorded pruritus characteristics, sociodemographic and …
Not all melanomas are created equal: A review and call for more research into nodular melanoma.
Among the histogenic subtypes of melanoma, nodular melanoma (NM) is the major contributor for thicker and fatal melanomas and it has been associated with melanoma-specific death in thin tumours highlighting …
Antiracism plan in dermatology.
The world has witnessed a crucial resurgence of racial equity movements following the highly publicized deaths of George Floyd, Breonna Taylor and Ahmaud Arbery, among others. This police violence re-exposed …