Cancer is caused by the accumulation of pathogenic alterations of the genome and epigenome that result in permanent changes that disrupt cellular homeostasis. The genes that become corrupted in this …
Melanoma pathology: new approaches and classification.
Cancer is caused by the accumulation of pathogenic alterations of the genome and epigenome that result in permanent changes that disrupt cellular homeostasis. The genes that become corrupted in this …
NOD2 signalling in hidradenitis suppurativa.
Hidradenitis suppurativa (HS) is associated with dysregulated immune responses including altered expression of cytokines, chemokines, and antimicrobial peptides and proteins (AMPs).To evaluate the expression of NOD2 and related factors in …
Health-related quality of life and economic burden of prurigo nodularis.
Prurigo nodularis (PN) is an understudied, pruritic inflammatory skin disease. Little is known about the effect of PN on quality of life (QoL) and its associated economic burden.To quantify QoL …
Association between PDCD1 gene polymorphisms and psoriasis susceptibility in the Chinese population.
As an immune regulator expressed on the surface of activated T cells, programmed cell death 1 (PDCD1) plays an important role in psoriasis. However, whether PDCD1 genetic polymorphism is associated …
Dermatological surgery: An update on suture materials and techniques: Part 1.
Significant variation exists in the surgical suture materials and techniques used for dermatological surgery. Many wound closure techniques are now practiced including use of sutures, staples and topical adhesives. The …
Intravascular histiocytosis: mimicker of cellulitis, angiosarcoma, inflammatory breast cancer, and others.
Intravascular histiocytosis is an underrecognized reactive skin condition characterized by the clinical finding of poorly demarcated erythematous to violaceous patches and plaques. The diagnosis is confirmed by the histologic findings …
Mycosis fungoides-derived exosomes promote cell motility, are enriched with miR-155 and miR-1246, and their plasma cell-free expression may serve as potential biomarkers for disease burden.
Literature regarding exosomes as mediators in intercellular communication to promote progression in mycosis fungoides (MF) is lacking.To characterize MF-derived exosomes and their involvement in the disease.Exosomes were isolated by ultracentrifugation …
Diagnosing muscle disease in a cohort of classic dermatomyositis patients seen at a rheumatologic dermatology outpatient clinic.
Existing criteria include muscle biopsies to improve the probability of capturing dermatomyositis (DM), but not much is known whether less invasive diagnostic procedures may be just as useful.We aim to …
Association of Single Nucleotide Polymorphisms in the CXCR1, CXCR2 and CXCL5 with the Behçet’s Disease in Denizli Province of Turkey.
Behçet’s disease (BD) is associated with the immune system, especially neutrophilic activity. The CXCR1, CXCR2 and CXCL5 mediate the activation and migration of the neutrophils.The aim of our study was …