Psoriasis is a chronic inflammatory skin disease requiring prolonged treatment. New biologic therapies require long-term evaluation to assess durability of their efficacy and safety profile over time.To evaluate long-term efficacy …
Impact of the COVID-19 pandemic on the diagnosis of new leprosy cases in Northeastern Brazil, 2020.
This study analyzed the impact of the COVID-19 pandemic on the detection of new cases of leprosy in the state of Bahia, Brazil. The periods January-September 2019 and January-September 2020 …
Glucocorticoids Promote CCL20 Expression in Keratinocytes.
Glucocorticoids (GC) are generally envisioned as immunosuppressive, but in conditions such as rosacea and perioral dermatitis they can lead to increased skin inflammation. In lung epithelia, GC promote expression of …
Dermatological surgery: An update on suture materials and techniques: Part 2.
This is the second part of a two-part series which summarises the latest evidence related to suture materials and wound closure techniques in dermatological surgery. We critically appraised evidence focusing …
Genodermatoses with Hearing impairment.
Hearing loss is a prominent feature in multiple genodermatoses. Underappreciation of auditory deficits can misdirect proper diagnosis by the treating dermatologist. This review sums up the anatomical, developmental, and embryological …
Tumor invasion in the hyponychium is associated with distant metastasis and poor prognosis in subungual melanoma: A histological landscape of 44 cases.
Subungual melanoma (SUM) has a poor prognosis due to delayed diagnosis. The progression, consensus on surgical treatment, correlation with clinical outcomes remains unclear.We aimed to identify the pattern of dermal …
Outcomes of Pregnancy and Childbirth in Women with Hidradenitis Suppurativa.
Many women affected by hidradenitis suppurativa (HS) are of childbearing age. To date, the literature is limited on pregnancy-related outcomes for women with HS.To investigate maternal and obstetric outcomes, and …
Late-onset adverse events under anti-PD1 therapy in melanoma patients: an observational study from MELBASE, a nationwide prospective cohort.
The purpose was to evaluate late-onset AEs in melanoma patients treated with anti-PD1 administered at least 2 years in a real-life setting. Patients were screened from MelBase (NCT02828202), a French …
Clinical characteristics and prognosis of acral lentiginous melanoma: a single-center series of 211 cases in China.
Acral lentiginous melanoma (ALM) is common in China with poor prognosis. However, there are only a few studies of ALM in the Asian population. We aimed to summarize and analyze …
Prevalence of Depression among Children, Adolescents, and Adults with Hidradenitis Suppurativa.
Information on prevalence of depression among children, adolescents and adults with hidradenitis suppurativa (HS) is limited.To compare prevalence of depression in HS patients with that of controls.Cross-sectional analysis of 38,140 …